Young Scholar TechTalk – High-throughput Cell Mechanics Characterization with Microfluidics
Cells can sense mechanical stimuli and convert them to biochemical signals for various specific cellular responses, such as stem cells differentiation, initiation of transcriptional programs, and cell migration. Cell mechanics focuses on the mechanical properties and behaviours of living cells and how cell mechanics relates to various cell functions. Currently, traditional cell mechanics measurement methods are cumbersome, low-throughput, and expensive to deploy. By exploiting microfluidic technology, Dr. Johnson Cui is investigating the cancer cell mechanics and developing an accurate, easy-to-use cell mechanics measurement platform for cell mechanics research and also for cancer diagnosis and therapeutics in the future.