Advancing optical label-free cellular imaging – from instrumentation to cell assays

Final Year ProjectDepartment of Electrical and Electronic Engineering

Project supervisor: Dr. K.K.M. Tsia (Department of Electrical and Electronic Engineering)

Quantitative phase imaging (QPI) is an advanced optical microscopy technique that requires no sample staining and allows quantitative measurement of biophysical parameters of the cell specimens. This technique is desirable especially in live-cell imaging, as it can yield cellular dry mass distribution, intracellular dynamics as well as size of cells with minimal intervention/damage to the sample. A compact and easily-compatible setup of QPI was developed and applied to a wide range of biomedical applications, ranging from fundamental biological studies in brain imaging, to the clinical studies in drug-screening for breast cancer cells and characterization of pathogenic bacteria biofilms.

Project leader: Chun ha Eun, BEng(MedE)

Team member(s): Le Thanh Hai Dang, Chui Mei Yee

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Winner of the Dean’s Fund Award @ The 1st Engineering InnoShow

This project team was selected for the Dean’s fund award at the 1st Engineering InnoShow. 

This team has received HK$10,000 sponsorship to participate in external competitions or incubation/ entrepreneurship/ startup programmes.