We are developing filtration technologies to benefit sustainable environment. The Center for Filtration Research (CFR) at the University of Minnesota, collaborating with 20 leading international filtration manufacturers and end users, was established to find filtration solutions to mitigate PM2.5 and other environmental pollutants. There are more than 15 on-going fundamental and applied research projects on air, gas and liquid filtration. Five projects will be presented: 1. reduction of aerosol concentration in classrooms to prevent virus transmissions; 2. electret and nanofiber media to improve filtration performance; 3. indoor air cleaning using gas purifiers, ionizers, and UV-C; 4. real-time image detection of airborne biological particles; 5. temperature resistant nano-scale membrane for enhanced ceramic wall-flow filter performance. Large scale air cleaning towers are established in Xi’an and Yancheng in China to mitigate urban air PM2.5and CO2 (Yancheng) with two additional towers in Delhi, India. All these research and development activities are helping to improve sustainable environment.